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Attenuated Vaccines for Augmented Immunity
Stylianos Bournazos1, Jeffrey V Ravetch1
1Laboratory of Molecular Genetics and Immunology, The Rockefeller University, New York, NY 10065, USA.
Abstract:
Live attenuated vaccines are more immunogenic and have the capacity to elicit long-lasting immune responses. In two recent studies, Wang et al. (2017) and Si et al. (2016) describe strategies for the generation of live attenuated influenza viruses, which elicited robust humoral, mucosal, and cellular immunity against diverse virus strains.
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