Related Experiment Video
Updated: Mar 6, 2026

Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology
Published on: December 15, 2017
Metabolic engineering for the microbial production of marine bioactive compounds
Xiangzhao Mao1, Zhen Liu2, Jianan Sun2
1Metabolic and Biomolecular Engineering National Research Laboratory, Department of Chemical and Biomolecular Engineering (BK21 Plus Program), BioProcess Engineering Research Center, Center for Systems and Synthetic Biotechnology, Institute for the BioCentury, KAIST, Daejeon, Republic of Korea; College of Food Science and Engineering, Ocean University of China, Qingdao, People's Republic of China.
Abstract:
Many marine bioactive compounds have medicinal and nutritional values. These bioactive compounds have been prepared using solvent-based extraction from marine bio-resources or chemical synthesis, which are costly, inefficient with low yields, and environmentally unfriendly. Recent advances in metabolic engineering allowed to some extent more efficient production of these compounds, showing promises to meet the increasing demand of marine natural bioactive compounds. In this paper, we review the strategies and statuses of metabolic engineering applied to microbial production of marine natural bioactive compounds including terpenoids and their derivatives, omega-3 polyunsaturated fatty acids, and marine natural drugs, and provide perspectives.
More Related Videos
Related Concept Videos
Bioremediation
Microbial Fermentation
Lipid Catabolism
Environmental Applications of Microorganisms
Amino Acid Catabolism
Biosynthesis in Bacteria

