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Diplopia and ptosis after diarrhea - A diagnostic challenge
Thomas Hasler1, Astrid Stückelberger2, Etienne Ott3
1Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland.
A woman experienced temporary double vision and eyelid drooping following a Campylobacter infection. These symptoms were diagnosed as Miller Fisher syndrome, a rare variant of Guillain Barré syndrome.
Area of Science:
- Neurology
- Infectious Diseases
Background:
- Guillain Barré syndrome (GBS) is an autoimmune disorder affecting the peripheral nervous system.
- Miller Fisher syndrome (MFS) is a rare variant of GBS characterized by ophthalmoplegia, ataxia, and areflexia.
Observation:
- A patient presented with acute onset of transient diplopia (double vision) and ptosis (eyelid drooping) of the left eye.
- The patient had a preceding history of Campylobacter infection.
Findings:
- The clinical presentation was consistent with Miller Fisher syndrome.
- The case highlights a potential link between Campylobacter infection and the development of MFS.
Implications:
- Campylobacter infections may serve as a trigger for autoimmune neurological disorders like MFS.
- Early recognition of MFS symptoms following infection is crucial for timely diagnosis and management.
- Further research is warranted to elucidate the precise pathophysiological mechanisms linking Campylobacter to MFS.
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