Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The arachidonic acid cascade: an immunologically based review.

C K Janniger1, S P Racis

  • 1Department of Medicine, UMDNJ New Jersey Medical School, Newark 07103-2757.

Journal of Medicine
|January 1, 1987
PubMed
Summary

This review explores how specific fatty acids are converted into eicosanoids, such as prostaglandins, thromboxanes, and leukotrienes. It details the crucial functions of these molecules within the immune system response.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Interdigital syphilis: a rare form of secondary syphilis.

International journal of STD & AIDS·2019
Same author

Milker's nodule: an occupational infection and threat to the immunocompromised.

Journal of the European Academy of Dermatology and Venereology : JEADV·2017
Same author

Vitiligo: recent insights and new therapeutic approaches.

Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia·2012
Same author

Pediculus humanus capitis: an update.

Acta dermatovenerologica Alpina, Pannonica, et Adriatica·2008
Same author

Dermatologic correlates of selected metabolic events.

Journal of medicine·2007
Same author

Oculocutaneous albinism.

Journal of the European Academy of Dermatology and Venereology : JEADV·2003

Area of Science:

  • Biochemistry
  • Immunology

Background:

  • Polyunsaturated 20-carbon fatty acids are precursors to important signaling molecules.
  • These molecules, known as eicosanoids, include prostaglandins (PGs), thromboxanes (TX), and leukotrienes (LTs).

Purpose of the Study:

  • To review the role of eicosanoids in the immune response.
  • To outline how various cells, particularly immunologic cells, release these metabolites.

Main Methods:

  • Literature review of existing research on eicosanoid metabolism and function.
  • Analysis of the biochemical pathways involved in eicosanoid synthesis.
  • Examination of the immunological roles of prostaglandins, thromboxanes, and leukotrienes.

Main Results:

  • Eicosanoids are critical mediators of immune cell function.
  • Different cell types synthesize and release specific eicosanoids in response to stimuli.
  • Eicosanoids modulate various aspects of the immune response, including inflammation and cell signaling.

Conclusions:

  • Eicosanoids play a multifaceted and essential role in orchestrating the immune system.
  • Understanding eicosanoid pathways offers potential targets for immunomodulatory therapies.

Related Experiment Videos