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Updated: Mar 6, 2026

Dissolution Dynamic Nuclear Polarization Instrumentation for Real-time Enzymatic Reaction Rate Measurements by NMR
Published on: February 23, 2016
Low-cost, pseudo-Halbach dipole magnets for NMR
Michael C D Tayler1, Dimitrios Sakellariou2
1Magnetic Resonance Research Center, Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK; Department of Physics, University of California, Berkeley, CA 94720, USA.
Abstract:
We present designs for compact, inexpensive and strong dipole permanent magnets aimed primarily at magnetic resonance applications where prepolarization and detection occur at different locations. Low-homogeneity magnets with a 7.5mm bore size and field up to nearly 2T are constructed using low-cost starting materials, standard workshop tools and only few hours of labor - an achievable project for a student or postdoc with spare time. As an application example we show how our magnet was used to polarize the nuclear spins in approximately 1mL of pure [13C]-methanol prior to detection of its high-resolution NMR spectrum at zero field (measurement field below 10-10T), where signals appear at multiples of the carbon-hydrogen spin-spin coupling frequency 1JCH=140.7(1)Hz.
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