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Updated: Aug 15, 2026

Acute Myocardial Infarction in Rats
Published on: February 16, 2011
Acute Myocardial Infarction following Naltrexone Consumption; a Case Report
Bita Dadpour1, Arash Gholoobi2, Shahrad Tajoddini3
1Addiction Research Centre, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.; Cardiac Anesthesia Research Centre, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
Abstract:
Cardiovascular effects of opioid withdrawal have long been studied. It was reported that patients with underlying ischemic heart disease and atherosclerotic vessels may be complicated by a sudden physical and emotional stress due to withdrawal syndrome. But some other believes sudden increase in catecholamine level as a sympathetic overflow might effect on heart with and without underlying ischemia. In the current study, a patient on methadone maintenance therapy (MMT) who experienced myocardial infarction (MI) after taking naltrexone was described.
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