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Updated: Mar 6, 2026

Performing In Vivo and Ex Vivo Electrical Impedance Myography in Rodents
Published on: June 8, 2022
[Electroimpedance Methods of Investigation of Cardiac Activity]
A I Malakhov1,2, A N Tikhomirov1,2, S I Shchukin1,2
1BMSTU, Moscow, Russia.
Aim:
of the present work was assessment of possibility to use modern electroimpedace methods for the study of activity of the heart. Electroimpemdace methods of measurement for many years remained in the shadow of other diagnostic methods because of low accuracy in evaluation of various parameters. At present, there are technologies of measurement which allow to carry out electroimpedance investigations of cardiac activity dynamically and with acceptable accuracy. In this article, we present methods of electroimpedace measurements created in Institute of Biomedical Equipment of N.E. Bauman Technical University. These methods allow to assess dynamics of movement of ventricles of the heart, to evaluate volume parameters of cardiac activity and all temporal phases of activity of cardiac chambers. We also present data of studies on healthy volunteers and patients of cardiological profile. It has been shown that patients with atrial fibrillation have substantially increased duration of electrical and mechanical activity of atria and ventricles as well as lowed ejection fraction compared with other participants of experiments.
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