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Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
[Factors Associated With Development of Atrial Fibrillation After Coronary Artery Bypass Grafting]
O A Rubanenko1,2, O V Fatenkov1,2, D V Kuznetsov1,2
1Samara State Medical University, Samara, Russia.
Insights
Older age, longer aortic cross-clamping time, larger left atrial size, and lower left ventricular ejection fraction increase the risk of atrial fibrillation after coronary artery bypass grafting surgery.
Area of Science:
- Cardiology
- Cardiac Surgery
- Electrophysiology
Background:
- Atrial fibrillation (AF) is a common complication following coronary artery bypass grafting (CABG).
- Identifying predictive factors for early postoperative AF is crucial for patient management and risk stratification.
Purpose of the Study:
- To determine the key factors associated with the development of atrial fibrillation (AF) in the early postoperative period after coronary artery bypass grafting (CABG).
Main Methods:
- A study involving 376 patients with ischemic heart disease undergoing CABG.
- Multivariate regression analysis and Receiver Operating Characteristic (ROC) analysis were employed to identify significant predictors.
Main Results:
- Atrial fibrillation (AF) occurred in 19.7% of patients, with significant associations found for age >59 years (OR 1.5), aortic cross-clamping time >43 min (OR 2.4), left atrial dimension >39 mm (OR 5.0), and left ventricular ejection fraction <51% (OR 3.6).
- Left atrial dimension >39 mm demonstrated high sensitivity (82%) for predicting AF, while left ventricular ejection fraction <51% showed high specificity (80%).
Conclusions:
- The development of early postoperative AF after CABG is influenced by patient age, left atrial size, left ventricular ejection fraction, and aortic cross-clamping duration.
- These factors can aid in risk assessment for AF development in patients undergoing CABG.
Purpose:
to identify factors associated with development of atrial fibrillation (AF) in the early postoperative period of coronary artery bypass grafting (CABG).
Methods:
A total of 376 patients with ischemic heart disease who underwent CABG were enrolled in the study.
Results:
During the observation period AF occurred in 74 patients (19.7%, 93% men, mean age 64.0+/-6.4 years), an average of 3.6+/-2 days after surgery. Multivariate regression analysis showed that odds ratio (OR) for AF in patients with age >59 years was 1.5 (95% confidence interval [CI], 1.1-3.5; p=0.04), aortic cross-clamping time >43 min - 2.4 (95% CI, 1.05-6.2; p=0.03), left atrial dimension (LAD) >39 mm - 5.0 (95% CI, 2.0-12.6; p=0.0006), left ventricular ejection fraction (LVEF) <51% - 3.6 (95% CI, 1.6-8.3, p=0.002). During ROC - analysis the high sensitivity was observed for LAD >39 mm (82%, =0.001), high specificity - for LVEF <51% (80%, =0.0009), highest positive likelihood ratio for LVEF <51% - 2.56 (=0.0009), greatest negative likelihood ratio for LAD >39 mm - 0.31 (=0.001).
Conclusion:
In our study, the risk of AF development in the early postoperative period of CABG depended on the patients age, left atrial size, left ventricular ejection fraction, and aortic cross-clamping time during CABG.
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