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Updated: Mar 6, 2026

Structural Information from Single-molecule FRET Experiments Using the Fast Nano-positioning System
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Nonlinear information fusion algorithms for data-efficient multi-fidelity modelling.

P Perdikaris1, M Raissi2, A Damianou3

  • 1Department of Mechanical Engineering , Massachusetts Institute of Technology , Cambridge, MA 02139, USA.

Proceedings. Mathematical, Physical, and Engineering Sciences
|March 16, 2017
PubMed
Summary
This summary is machine-generated.

This study introduces a new probabilistic framework for multi-fidelity modeling, enhancing accuracy by learning complex correlations between models of varying fidelity. It effectively safeguards against inaccurate low-fidelity models, improving computational efficiency.

Keywords:
Bayesian inferenceGaussian processesdeep learninguncertainty quantification

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Last Updated: Mar 6, 2026

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Area of Science:

  • Computational Science
  • Data Science
  • Engineering

Background:

  • Multi-fidelity modeling combines low-cost and high-fidelity data for accurate predictions.
  • Existing methods rely on strong correlations, but low-fidelity models can be inaccurate outside specific parameter ranges.

Purpose of the Study:

  • To develop a probabilistic framework for multi-fidelity modeling that learns complex, nonlinear cross-correlations.
  • To safeguard against erroneous predictions from low-fidelity models outside their validity regime.
  • To extend existing linear autoregressive methodologies with enhanced capabilities.

Main Methods:

  • Utilizes Gaussian process regression and nonlinear autoregressive schemes.
  • Learns space-dependent cross-correlations between models of variable fidelity.
  • Integrates low-fidelity model outputs with high-fidelity observations.

Main Results:

  • Demonstrates effective learning of complex nonlinear and space-dependent cross-correlations.
  • Successfully safeguards against low-fidelity models providing wrong trends.
  • Achieves significant computational gains compared to high-fidelity-only approaches.

Conclusions:

  • The proposed framework offers a fundamental extension to multi-fidelity information fusion algorithms.
  • Maintains algorithmic complexity and computational cost similar to existing linear methods.
  • Validated on synthetic and real-world computational fluid dynamics datasets.