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High-resolution fiber-optic dosimeters for microbeam radiation therapy.

James Archer1, Enbang Li1, Marco Petasecca1

  • 1Centre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW, 2522, Australia.

Medical Physics
|March 16, 2017
PubMed
Summary

A novel plastic scintillator and optical fiber dosimeter achieves high spatial resolution for accurate x-ray dose measurements. This water-equivalent probe is ideal for microbeam radiation therapy quality assurance.

Keywords:
fiber-optic dosimetrymicrobeam radiation therapyscintillatorsx-ray

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Area of Science:

  • Medical Physics
  • Radiation Detection and Measurement

Background:

  • Accurate dose measurement is critical in radiation therapy, especially for advanced techniques like microbeam radiation therapy.
  • Existing dosimeters may lack the necessary spatial resolution or water equivalence for precise measurements in small radiation fields.

Purpose of the Study:

  • To develop and evaluate a high-resolution, water-equivalent, optical, and passive x-ray dosimeter.
  • To assess the dosimeter's suitability for applications requiring precise dose measurements, such as synchrotron x-ray microbeam radiation therapy.

Main Methods:

  • A 100 μm plastic scintillator was optically coupled to a 1 mm optical fiber.
  • Background Cherenkov radiation was measured and subtracted using a reference fiber.
  • The dosimeter's performance was tested using a 6 MV LINAC x-ray beam, measuring beam and depth dose profiles.

Main Results:

  • The dosimeter achieved a peak edge-on spatial resolution of 100 μm.
  • Measured beam profiles and key parameters (penumbra width, percent depth dose) closely matched ionization chamber data.
  • The system demonstrated good agreement with established dosimetry methods.

Conclusions:

  • A scintillation and optical fiber system can achieve high spatial resolution for x-ray dosimetry.
  • The developed probe is water-equivalent, passive, energy-independent, radiation-hard, and cost-effective.
  • This dosimeter shows significant potential for improving quality assurance in microbeam radiation therapy.