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Published on: April 17, 2021
Complete Versus Incomplete Angiography Prior to Percutaneous Coronary Intervention in ST-Elevation Myocardial
Kevin Stiver, Xu Gao, Satya Shreenivas
1Ohio State University Heart and Vascular Center, 473 W. 12th Avenue, Suite 200, Columbus, OH 43210-1252 USA. scott.lilly@osumc.edu.
Insights
Incomplete angiography (IA) before percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI) shortens door-to-balloon times. However, this approach did not improve short-term patient outcomes in this study.
Area of Science:
- Cardiology
- Interventional Cardiology
- Acute Coronary Syndromes
Background:
- Shorter reperfusion times in ST-elevation myocardial infarction (STEMI) are linked to better survival rates.
- Prehospital strategies aim to reduce door-to-balloon (DTB) time, but interventions within the catheterization lab are less studied.
- Incomplete angiography (IA) is a strategy used to potentially decrease DTB time before percutaneous coronary intervention (PCI).
Purpose of the Study:
- To evaluate if STEMI patients undergoing IA before PCI have different preprocedural characteristics.
- To determine if IA prior to PCI impacts post-PCI outcomes in STEMI patients.
- To compare outcomes between STEMI patients who received IA versus complete angiography (CA) before PCI.
Main Methods:
- Retrospective review of 256 STEMI patients from March 2013 to December 2015.
- Comparison of clinical, demographic, and angiographic data between IA and CA groups.
- Analysis of variance used to compare predictors and outcomes, focusing on DTB times.
Main Results:
- IA was performed in 26.6% of patients; IA patients were younger.
- DTB times were significantly shorter in the IA group (28.1 min) compared to the CA group (37.3 min).
- No significant differences were observed in peak troponin, length of stay, in-hospital mortality, or discharge ejection fraction between groups.
Conclusions:
- IA is associated with reduced DTB times in STEMI patients undergoing PCI.
- Despite shorter DTB times, IA did not demonstrate improved short-term clinical outcomes in this patient population.
- Further research may be needed to clarify the role and impact of IA in STEMI management.
Objectives:
Shorter reperfusion times in ST-elevation myocardial infarction (STEMI) are associated with improved survival. Prehospital strategies have been developed to minimize door-to-balloon (DTB) time, but few strategies within the catheterization laboratory itself have been evaluated. Incomplete angiography (IA) prior to percutaneous coronary intervention (PCI) is undertaken in clinical practice as a means to further reduce DTB time. We sought to determine whether or not those with STEMI who underwent IA prior to PCI had different preprocedural characteristics or post-PCI outcomes.
Methods:
We retrospectively reviewed patients presenting to our institution between March 2013 and December 2015. Clinical, demographic, and angiographic data were reviewed. The frequency, predictors, and outcomes among those who received IA vs complete angiography (CA) prior to PCI were compared with analysis of variance.
Results:
Two hundred fifty-six patients were identified; 68 patients (26.6%) underwent IA and 188 patients (73.4%) had CA prior to PCI. Patients who received IA were younger, but no other preprocedural factors were predictive of IA. The practice of IA did vary by operator (range, 0%-47%; P<.01). DTB times were shorter in the IA group (28.1 min vs 37.3 min; P<.01). Overall outcomes, including peak troponin values, length of stay, in-hospital mortality, and discharge ejection fraction did not differ between the groups.
Conclusion:
IA is associated with shorter DTB times, although in this population was not associated with improvements in short-term outcomes.
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