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Related Experiment Video

Updated: Mar 6, 2026

Vascularized Composite Hand Allograft Procurement and Preparation for Distal and Proximal Forearm Allotransplantation: A Stepwise Approach
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Forearm versus upper arm grafts for vascular access.

Shawn M Gage1,2, Jeffrey H Lawson3,4

  • 1Clinical Operations, Humacyte, Inc., Morrisville, NC - USA.

The Journal of Vascular Access
|March 16, 2017
PubMed
Summary
This summary is machine-generated.

Forearm and upper arm arteriovenous grafts show similar patency and complication rates. Pre-operative planning is crucial for successful placement, considering patient-specific factors for optimal outcomes.

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Area of Science:

  • Vascular Surgery
  • Nephrology
  • Dialysis Access

Background:

  • Arteriovenous grafts (AVGs) are critical for hemodialysis access.
  • Choosing between forearm and upper arm AVG placement involves evaluating patency and complication risks.

Purpose of the Study:

  • To compare the efficacy and safety of forearm versus upper arm arteriovenous grafts.
  • To identify key factors influencing the clinical success of AVG placement.

Main Methods:

  • Comparative analysis of patency rates (primary and secondary) at 1 and 2 years.
  • Assessment of complication profiles between forearm and upper arm AVG groups.
  • Emphasis on pre-operative evaluation including patient history, physical examination, and venous imaging.

Main Results:

  • Similar primary patency at 1 year for forearm (22%-50%) and upper arm (22%-42%) grafts.
  • Secondary patency at 1 year: forearm (78%-89%) vs. upper arm (52%-67%).
  • Secondary patency at 2 years: forearm (30%-64%) vs. upper arm (35%-60%).
  • Operative strategies and complication risks are comparable between both locations.

Conclusions:

  • Forearm and upper arm arteriovenous grafts demonstrate comparable performance regarding patency and complications.
  • Clinical success hinges on thorough pre-operative planning, individualized assessment, and consideration of prior access history.
  • Minimizing steal syndrome risk involves strategic inflow artery selection, such as the proximal radial or ulnar artery.