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Related Concept Videos

Instrument Calibration01:12

Instrument Calibration

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Instrument calibration is essential for ensuring that instruments produce accurate and consistent results. It is vital in manufacturing, healthcare, testing laboratories, and scientific research. Calibration processes are specific to each instrument and help enhance data accuracy. Each instrument has a unique calibration process tailored to its design and function to improve data accuracy.
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A calibration curve is a plot of the instrument's response against a series of known concentrations of a substance. This curve is used to set the instrument response levels, using the substance and its concentrations as standards. Alternatively, or additionally, an equation is fitted to the calibration curve plot and subsequently used to calculate the unknown concentrations of other samples reliably.
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The Earth's shape is best described as an ellipsoid, a slightly flattened sphere created by rotating an ellipse around its minor axis. This flattening results in the polar axis being about 21 kilometers shorter than the equatorial axis. In contrast, the geoid represents the Earth's gravitational shape and aligns with the mean sea level (MSL). The geoid is an irregular equipotential surface where gravity is perpendicular at every point. Variations in Earth's mass distribution cause geoid...
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Root loci often diverge as system poles shift from the real axis to the complex plane. Key points in this transition are the breakaway and break-in points, indicating where the root locus leaves and reenters the real axis. The branches of the root locus form an angle of 180/n degrees with the real axis, where n is the number of branches at a breakaway or break-in point.
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Related Experiment Video

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Three-dimensional Super Resolution Microscopy of F-actin Filaments by Interferometric PhotoActivated Localization Microscopy iPALM
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Evaluation of a surface imaging system's isocenter calibration methods.

Adam B Paxton1, Ryan P Manger2, Todd Pawlicki2

  • 1Department of Radiation Oncology, University of Utah, Huntsman Cancer Hospital, Salt Lake City, UT, 84112, USA.

Journal of Applied Clinical Medical Physics
|March 17, 2017
PubMed
Summary

The Isocentre Calibration (IC) method for the AlignRT system effectively corrects positioning errors caused by misaligning the calibration plate during Monthly Calibration (MC). This ensures accurate patient alignment in radiotherapy.

Keywords:
isocenter calibrationoptical surface imagingstereotactic radiosurgery

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Area of Science:

  • Medical Physics
  • Radiotherapy Technology
  • Image-Guided Therapy

Background:

  • AlignRT is a surface imaging system for patient positioning in radiotherapy.
  • Two calibration methods exist: Monthly Calibration (MC) using a plate, and Isocentre Calibration (IC) using a plate and cubic phantom with the linac beam.
  • Misalignment during MC can introduce positioning errors.

Purpose of the Study:

  • To evaluate the impact of calibration plate misalignment during MC on AlignRT system accuracy.
  • To compare the effectiveness of MC and IC in mitigating these miscalibration errors.
  • To assess the accuracy of AlignRT during simulated stereotactic radiosurgery (SRS) treatments.

Main Methods:

  • The calibration plate was intentionally shifted ±3.0 mm (longitudinal/lateral) and ±1.0 mm (longitudinal/lateral/vertical) from isocenter during MC.
  • A mock SRS treatment was performed using an anthropomorphic head phantom monitored by AlignRT at various couch angles.
  • The IC procedure was repeated after each MC misalignment, and results were compared.

Main Results:

  • Longitudinal and lateral shifts of ±3.0 mm and ±1.0 mm in MC resulted in average indicated offsets of 4.3 mm and 1.6 mm at ±90° couch rotation, respectively.
  • Vertical shifts had minimal impact on offsets due to their alignment with the couch rotation axis.
  • After applying IC, all indicated offsets were within 0.5 mm across all couch angles and miscalibrations.

Conclusions:

  • The Isocentre Calibration (IC) method effectively compensates for positioning errors introduced by calibration plate misalignments during Monthly Calibration (MC).
  • IC ensures sub-millimeter accuracy, mitigating artifacts from MC plate misalignments and confirming accuracy within the known couch walkout magnitude.
  • IC is a robust method for maintaining AlignRT system accuracy in image-guided radiotherapy.