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Preparation of DMMTAV and DMDTAV Using DMAV for Environmental Applications: Synthesis, Purification, and Confirmation
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Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement

Matthew Butawan1, Rodney L Benjamin2, Richard J Bloomer3

  • 1Center for Nutraceutical and Dietary Supplement Research, School of Health Studies, The University of Memphis, Memphis, TN 38152, USA. mbbtawan@memphis.edu.

Nutrients
|March 17, 2017
PubMed

Insights

Methylsulfonylmethane (MSM) is a popular supplement for reducing inflammation and pain. It is safe and well-tolerated, with ongoing research to optimize dosage for maximum health benefits.

Area of Science:

  • Nutritional Science
  • Supplement Research

Background:

  • Methylsulfonylmethane (MSM) is a widely used dietary supplement.
  • Its primary application is as an anti-inflammatory agent.

Purpose of the Study:

  • To review the common uses and applications of MSM as a dietary supplement.
  • To detail the safety profile of MSM consumption.

Main Methods:

  • Review of existing animal models.
  • Analysis of human clinical trials and experiments.

Main Results:

  • MSM supplementation improves inflammation, joint/muscle pain, oxidative stress, and antioxidant capacity.
  • Evidence suggests optimal dosing and treatment timelines are still under investigation.
  • MSM is Generally Recognized As Safe (GRAS) and well-tolerated up to 4g/day with mild side effects.

Conclusions:

  • MSM is a safe and effective supplement for various health benefits.
  • Further research is needed to establish precise optimal dosage and treatment protocols.
Keywords:
MSMdimethyl sulfoneinflammationjoint painmethylsulfonylmethane

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