Chronic Mesenteric Ischemia: Patient Outcomes Using Open Surgical Revascularization

Area of Science:

• Gastrointestinal Surgery
• Vascular Surgery
• Ischemia Research

Background:

• Chronic mesenteric ischemia (CMI) is a rare but serious condition.
• Open treatment (OT) remains a viable option for CMI management.
• Analysis of patient outcomes and quality of life after OT is crucial.

Purpose of the Study:

• To evaluate patient outcomes following open treatment for CMI.
• To assess the health-related quality of life (HRQoL) in CMI patients treated with OT.
• To investigate the impact of simultaneous revascularization of the celiac trunk (TC) and superior mesenteric artery (SMA) on mortality.

Main Methods:

• Retrospective analysis of patient data from 2001 to 2014.
• Kaplan-Meier analysis for mortality and patency rates.
• Utilized the 36-item health survey for HRQoL assessment.

Main Results:

• 100 patients included: TC (n=23), SMA (n=26), both (n=51).
• 1-year survival rates ranged from 75% (TC) to 96% (both TC/SMA). 5-year survival showed variations. Obesity and hospital stay length impacted survival.
• 1-year primary patency rates varied by vessel (TC: 60%, SMA: 86%, both: 71%), with higher secondary rates. HRQoL was significantly lower than German normative data.

Conclusions:

• Open treatment for CMI is a safe procedure.
• Simultaneous revascularization of TC and SMA does not negatively impact mortality.
• Open treatment for CMI does not necessarily lead to improved HRQoL.