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Essential Tremor with Aspartic Acidemia.

Shiroh Miura1, Ryuta Fujioka2, Takayuki Taniwaki1

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The Kurume Medical Journal
|March 18, 2017
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Summary

Essential tremor may be detected using amino acid biomarkers. This preliminary report suggests aspartic acid and glutamic acid levels could aid in essential tremor diagnosis.

Keywords:
amino acidaspartic acidessential tremorglutamic acidtaurine

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Area of Science:

  • Neurology
  • Biochemistry

Background:

  • Essential tremor is a common neurological disorder.
  • The exact pathophysiology of essential tremor remains unclear.

Observation:

  • Two cases of essential tremor presented with aspartic acidemia.
  • These patients also exhibited mildly elevated plasma glutamic acid concentrations.

Findings:

  • The study observed a correlation between essential tremor and specific amino acid imbalances.
  • Aspartic acidemia and increased plasma glutamic acid were noted in the cases.

Implications:

  • Amino acids, such as aspartic acid, may serve as potential biomarkers for essential tremor.
  • Further research is warranted to validate these findings for diagnostic purposes.