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Bilateral lacrimal caruncle lesions.
Yuta Okumura1, Yoshiko Takai1, Shunsuke Yasuda1
1Department of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Nagoya Journal of Medical Science
|March 18, 2017
Summary
This study investigated lesions on the medial lacrimal canthus in a patient with perinuclear anti-neutrophil cytoplasmic antibody-positive interstitial pneumonia. Histopathology revealed sebaceous gland hyperplasia and inflammation, with a possible link to steroid use or infection.
Area of Science:
- Ophthalmology
- Dermatology
- Rheumatology
Background:
- A 65-year-old male patient presented with bilateral medial lacrimal canthus lesions.
- The patient had a history of perinuclear anti-neutrophil cytoplasmic antibody (pANCA)-positive interstitial pneumonia.
Observation:
- Orbital MRI ruled out space-occupying lesions; thyroid disease was also excluded.
- Surgical excision of the masses was performed for diagnostic purposes.
Findings:
- Histopathological examination revealed sebaceous gland hyperplasia and periglandular inflammation.
- A retention cyst, potentially infection-related, was noted in the left eye specimen.
- Steroid use was considered a possible contributing factor to lesion development.
Implications:
- The findings suggest a complex etiology for lacrimal canthus lesions in patients with autoimmune conditions.
- While a direct link between ANCA and the lesions was not definitively established, it remains a possibility.
- Further research may elucidate the relationship between systemic inflammatory diseases and ocular adnexal findings.
Keywords:
inflammationinterstitial pneumonialacrimal caruncleperinuclear anti-neutrophil cytoplasmic antibodies (pANCA)sebaceous gland
