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Updated: Mar 6, 2026

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[Clinical study on the corneal epithelial dysfunction after cataract extraction].

J H Qu1, Z Q Wang, Y Zhang

  • 1Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University; Beijing Ophthalmology & Visual Sciences Key Laboratory. Beijing 100005, China.

[Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology
|March 21, 2017
PubMed
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Cataract surgery can cause corneal epithelial dysfunction, presenting as edema and staining. Prompt treatment with protective eye medications ensures complete recovery and favorable outcomes.

Area of Science:

  • Ophthalmology
  • Corneal Disease
  • Surgical Complications

Background:

  • Cataract extraction is a common surgical procedure.
  • Corneal epithelial dysfunction is a potential post-operative complication.

Purpose of the Study:

  • To investigate the clinical features, diagnosis, and treatment of corneal epithelial dysfunction following cataract extraction.
  • To analyze in vivo laser confocal microscopy findings in affected patients.

Main Methods:

  • Retrospective analysis of 15 cases of corneal epithelial dysfunction post-cataract extraction.
  • Evaluation of clinical manifestations, confocal microscopy images, and treatment outcomes.

Main Results:

  • Common manifestations included increased epithelial permeability, edema, dot staining, defects, and ulceration.
Keywords:
Cataract extractionCorneal edemaCorneal opacityCorneal ulcerEpithelium, cornealPostoperative complications

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  • Confocal microscopy revealed altered basal cell nuclei, abnormal structure, reduced density, and a disordered sub-basal nerve plexus.
  • All patients achieved complete recovery with protective and healing-promoting therapies.

    • Conclusions:

    • Early signs of post-cataract extraction corneal epithelial dysfunction are corneal edema and dot staining.
    • Delayed intervention can lead to severe complications like filamentous keratitis and corneal ulcers.
    • Timely application of corneal epithelial protective agents is crucial for a positive prognosis.