Simultaneous total cavopulmonary connection and cardiac re-synchronisation therapy.
Keisuke Nakanishi1, Shiori Kawasaki1, Atsushi Amano1
1Department of Cardiovascular Surgery,School of Medicine,Juntendo University,Tokyo,Japan.
Cardiology in the Young
|March 21, 2017
Summary
This study presents the first simultaneous use of cardiac resynchronization therapy and total cavopulmonary connection for heart failure. The combined approach successfully improved patient synchrony and cardiac function.
Area of Science:
- Cardiology
- Pediatric Cardiac Surgery
- Medical Technology
Background:
- Congenital heart defects often require complex surgical interventions.
- Cardiac dyssynchrony and heart failure present significant management challenges.
- Total cavopulmonary connection (TCPC) is a palliative procedure for single-ventricle physiology.
Observation:
- A patient with significant cardiac dyssynchrony, wide QRS complex, and heart failure was considered for combined therapy.
- Simultaneous implantation of cardiac resynchronization therapy (CRT) alongside TCPC was performed.
- This combined approach represents a novel therapeutic strategy.
Findings:
- Post-procedure, the patient demonstrated significant improvement in QRS width.
- Brain natriuretic peptide levels, a marker of cardiac strain, were reduced.
- Speckle tracking echocardiography confirmed enhanced synchrony of ventricular wall motion.
Implications:
- Simultaneous CRT and TCPC may be a viable option for select patients with complex congenital heart disease and heart failure.
- This approach offers potential for improved cardiac function and synchrony.
- Further research is warranted to establish the long-term efficacy and safety of this combined therapy.
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