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Berberine Derivatives with Different Pharmacological Activities via Structural Modifications

Daipeng Xiao1, Zhenbao Liu2, Shanshan Zhang1

  • 1Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China.

Mini Reviews in Medicinal Chemistry
|March 23, 2017
PubMed
Summary

Berberine, a natural compound, shows promise but has poor bioavailability. Chemical modifications are being explored to enhance its pharmacological properties and overcome limitations for wider application.

Keywords:
Berberinebioavailabilitychemical transformationmechanismspharmacological activitiesstructural modification.

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