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Published on: November 21, 2023
Rapidly destructive osteoarthritis can mimic infection
1Department of Orthopaedic Surgery, Carolinas Medical Center, Charlotte, NC, USA.
Abstract:
The intraoperative appearance of rapidly destructive osteoarthritis and septic arthritis can be similar. Three patients at our institution demonstrated preoperative or intraoperative findings potentially consistent with infection during primary total hip arthroplasty; however, none of these patients were found to have an actual infection. One of these patients underwent an unnecessary 2-stage total hip arthroplasty secondary to the intraoperative appearance of their joint fluid. We advocate performing an infection workup preoperatively when patients present with rapid degenerative changes of their hip joint to diminish the uncertainty of proceeding with arthroplasty.
Insights
Rapidly destructive osteoarthritis and septic arthritis can appear similar during hip surgery. Preoperative infection workups are recommended for hip joint degeneration to prevent unnecessary procedures.
Area of Science:
- Orthopedic Surgery
- Infectious Disease
- Rheumatology
Background:
- Distinguishing between rapidly destructive osteoarthritis (RDOA) and septic arthritis intraoperatively can be challenging.
- Both conditions may present with similar joint fluid characteristics and inflammatory signs.
- Accurate diagnosis is crucial for appropriate patient management and treatment planning.
Observation:
- Three patients undergoing primary total hip arthroplasty (THA) presented with findings suggestive of infection.
- These findings included changes in joint fluid appearance and rapid joint degeneration.
- However, subsequent laboratory analysis confirmed the absence of septic arthritis in all cases.
Findings:
- One patient underwent a 2-stage THA due to the intraoperative suspicion of infection, which was later found to be unnecessary.
- The intraoperative appearance of joint fluid in RDOA can mimic that of septic arthritis.
- Misdiagnosis can lead to suboptimal treatment and increased patient morbidity.
Implications:
- Preoperative infection workup is essential for patients with rapid degenerative hip changes before THA.
- Implementing a standardized preoperative protocol can reduce diagnostic uncertainty.
- This approach aims to prevent unnecessary surgical interventions and improve patient outcomes in total hip arthroplasty.

