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Updated: Mar 5, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
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Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

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Pediatric Antimicrobial Stewardship Programs

Kristen Nichols, Sylvia Stoffella, Rachel Meyers

    The Journal of Pediatric Pharmacology and Therapeutics : JPPT : the Official Journal of PPAG
    |March 25, 2017
    PubMed

    Insights

    Pediatric antimicrobial stewardship programs are crucial for combating rising multidrug-resistant infections in children. The Pediatric Pharmacy Advocacy Group (PPAG) advocates for their implementation, inclusion of specialists, and legislative support.

    Area of Science:

    • Pediatrics
    • Infectious Diseases
    • Antimicrobial Resistance

    Background:

    • Frequent antimicrobial use in children has accelerated multidrug-resistant bacterial infections.
    • Pediatric antimicrobial stewardship programs (ASPs) are vital due to unique patient needs and risks.
    • Children face increased vulnerability to resistance and adverse events from antibiotic exposure.

    Purpose of the Study:

    • To present the Pediatric Pharmacy Advocacy Group's (PPAG) position statement on pediatric antimicrobial stewardship.
    • To advocate for the implementation and comprehensive support of pediatric ASPs.
    • To recommend specific legislative and policy actions to enhance antibiotic stewardship in children.

    Main Methods:

    • This paper is a position statement from the Pediatric Pharmacy Advocacy Group (PPAG).
    • It outlines PPAG's stance on the necessity and components of pediatric antimicrobial stewardship.
    • Recommendations are based on the unique aspects of pediatric antimicrobial use and resistance.

    Main Results:

    • PPAG strongly supports the implementation of ASPs for all pediatric patients.
    • PPAG emphasizes the need for pediatric pharmacy specialists within these programs.
    • PPAG calls for insurance coverage and legislative action to support pediatric stewardship.

    Conclusions:

    • Pediatric-focused antimicrobial stewardship is essential to combat resistance and improve patient safety.
    • Integration of pediatric pharmacy specialists and supportive policies are critical for effective ASPs.
    • PPAG advocates for legislative mandates and dedicated federal task forces to address pediatric antibiotic resistance.

    Keywords:
    antimicrobial resistanceantimicrobial stewardshipinfection managementinfection prevention stewardshippharmacy educationresidents

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