Raising Public Awareness of Clinical Trials: Development of Messages for a National Health Communication Campaign

Holly A Massett1, David M Dilts2, Robert Bailey3

  • 1a Cancer Therapy Evaluation Program, Division of Cancer Treatment & Diagnosis , National Cancer Institute , Bethesda , Maryland , USA.

Insights

To boost clinical trial participation, messages should highlight self-interest and normalize trials as routine, state-of-the-art care. Engaging healthcare providers is key for patient awareness and recruitment.

Area of Science:

  • Clinical research
  • Public health communication
  • Patient recruitment

Background:

  • Clinical trials are crucial for medical advancement but often fail recruitment goals.
  • Low participation rates hinder the development of new treatments and patient quality of life.

Purpose of the Study:

  • To identify effective communication messages for a national campaign to increase clinical trial awareness and interest.
  • To understand motivations and concerns of the public and primary care physicians regarding clinical trial participation.

Main Methods:

  • Formative research conducted with two key populations: the general public and primary care physicians.
  • Qualitative analysis to identify key themes and message preferences for a communication campaign.

Main Results:

  • Participants are motivated by self-interest and the desire for personal health benefits.
  • Messages normalizing clinical trials as standard, state-of-the-art care reduce concerns.
  • Clear, concise messaging with actionable steps and relatable portrayals are preferred.
  • Healthy audiences showed lower interest, indicating a need for targeted approaches.

Conclusions:

  • Tailored messaging is essential to effectively recruit participants for clinical trials.
  • Engaging primary care physicians is a critical strategy to enhance patient awareness and participation.
  • Communication campaigns should focus on self-benefit, hope, and clear calls to action.

Related Concept Videos

Clinical Trials: Overview01:11

Clinical Trials: Overview

Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
5.2K
Clinical Trials01:16

Clinical Trials

Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
11.0K
Preclinical Development: Overview01:28

Preclinical Development: Overview

Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. There are four main phases to this process. First, safety pharmacology tests are conducted to ensure the drug does not produce any acutely harmful effects. These tests examine parameters such as bronchoconstriction, cardiac dysrhythmias, blood pressure changes, and ataxia. Next, preliminary toxicological testing is performed to determine the...
6.2K
Pharmacovigilance01:19

Pharmacovigilance

Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
1.9K
Levels of Health Promotion and Illness Prevention01:26

Levels of Health Promotion and Illness Prevention

Health promotion allows a person to control the determinants of health, resulting in an improved health status. It enhances the quality of life and reduces premature deaths. Health promotion and illness prevention programs help people make beneficial choices to reduce the risk of disease and disabilities. There are three health promotion and illness prevention levels: primary, secondary, and tertiary prevention.
In primary prevention, actions taken before disease onset prevent the disease from...
15.3K
Role of Communication in the Nursing Process II: Planning and Implementation01:25

Role of Communication in the Nursing Process II: Planning and Implementation

Several factors are considered while creating a patient's care plan. Motivation is a factor in improving communication, and patients often require encouragement to try different approaches involving significant change. It is essential to involve the patient and family in decisions about the plan of care to determine whether the suggested methods are acceptable. Consider meeting critical comfort and safety needs before introducing new communication methods and techniques. Allow adequate time...
2.8K