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A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
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Discovery of Novel Gq-Biased LPA1 Negative Allosteric Modulators

Yuji Shimizu1, Masaharu Nakayama1

  • 11 Biomolecular Research Laboratories, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Fujisawa, Japan.

SLAS Discovery : Advancing Life Sciences R & D
|March 28, 2017
PubMed

Keywords:
biased ligandimpedance assaylysophosphatidic acidlysophosphatidic acid receptor 1negative allosteric modulator

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