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Does preoperative depression predict post-operative surgical pain: A systematic review
Anali Dadgostar1, Mark Bigder1, Nahid Punjani1
1Harvard T.H. Chan School of Public Health, 677 Huntington Ave, Boston, MA 02115, USA.
International Journal of Surgery (London, England)
|April 1, 2017
Summary
Pre-operative depression
Area of Science:
- Psychosocial influences on surgical outcomes
- Pain management and surgical recovery
Background:
- Surgical outcomes are influenced by various factors, including psychosocial elements.
- Understanding pre-operative depression's impact on post-operative pain is crucial for improving surgical care.
Purpose of the Study:
- To systematically review randomized-control trials and observational studies.
- To examine the relationship between pre-operative depression and post-operative pain outcomes within six weeks.
Main Methods:
- Searched major databases (PubMed, EMBASE, CINAHL, Web of Science) for studies from 2006-2016.
- Included adult surgical patients with pre-operative depression, assessing post-operative pain via scales and medication use.
- Conducted a qualitative summary due to significant heterogeneity, precluding meta-analysis.
Main Results:
- 18 studies met inclusion criteria; 8 showed a significant effect of pre-operative depression on post-operative pain (1314 patients).
- 10 studies found no statistically significant effect (1226 patients).
- Significant clinical and statistical heterogeneity was noted across studies.
Conclusions:
- The evidence is limited by study heterogeneity and poor data quality.
- Further large-scale epidemiologic studies are needed to clarify the impact of pre-operative depression on post-operative pain.