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A Case of Risperidone Induced Stuttering as a Paradox
İnci Meltem Atay1, Bilal Tanritanir1, Abdullah Akpinar1
1Department of Psychiatry, Süleyman Demirel University Faculty of Medicine, Isparta, Turkey.
Noro Psikiyatri Arsivi
|April 1, 2017
Summary
This study reports a rare case of stuttering as an adverse effect of chronic low-dose risperidone treatment. This paradoxical effect is notable, as risperidone is sometimes used to treat stuttering.
Area of Science:
- Neuroscience
- Pharmacology
- Speech-Language Pathology
Background:
- Stuttering involves disruptions in speech timing and fluency.
- Acquired stuttering can be a rare side effect of certain medications.
- Risperidone, an antipsychotic, antagonizes dopamine D2 and serotonin 5-HT2A receptors.
Observation:
- The study presents a unique case of stuttering induced by chronic low-dose risperidone.
- Previous literature documented only two cases of stuttering linked to short-term, high-dose risperidone in patients with psychotic disorders.
Findings:
- This is the first reported instance of stuttering as an adverse effect of chronic low-dose risperidone.
- The findings highlight a paradoxical relationship between risperidone's use and its potential to induce stuttering.
Implications:
- Clinicians should be aware of stuttering as a potential, albeit rare, adverse effect of long-term risperidone therapy.
- Further research is needed to understand the mechanisms behind risperidone-induced stuttering.
- This case challenges the conventional understanding of risperidone's effects on speech fluency.