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Related Experiment Videos

Exploring new packaging and delivery options for the immunization supply chain.

Darin Zehrung1, Courtney Jarrahian1, Birgitte Giersing2

  • 1PATH, 2201 Westlake Avenue, Suite 200, Seattle, WA 98121, USA.

Vaccine
|April 3, 2017
PubMed
Summary

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Innovative vaccine packaging and delivery technologies, including novel devices and formulations, can enhance immunization supply chains. Early stakeholder engagement and consideration of factors like cold chain and cost are crucial for successful program integration.

Area of Science:

  • Vaccinology
  • Pharmaceutical Technology
  • Supply Chain Management

Background:

  • The immunization supply chain can be improved by various vaccine packaging and delivery technologies.
  • These include primary packaging innovations like blow-fill-seal containers and novel delivery systems such as intradermal devices, microarray patches, and sublingual vaccines.

Purpose of the Study:

  • To review emerging vaccine packaging and delivery technologies.
  • To assess their potential impact on immunization supply chains.
  • To identify key considerations for their programmatic suitability and timelines for availability.

Main Methods:

  • Review of existing and developmental vaccine packaging and delivery technologies.
  • Analysis of timelines for technological availability based on development stage and licensure requirements.
Keywords:
Cold chainDelivery deviceImmunization supply chainIntradermal injectionsPackagingSublingual administration

Related Experiment Videos

  • Identification of factors influencing programmatic suitability for immunization programs.

    • Main Results:

    • Some technologies, like intradermal devices for inactivated poliovirus vaccine, are expected by 2017 to address supply limitations.
    • Other technologies, such as microarray patches and sublingual vaccines, may be available long-term (2021+).
    • Successful development necessitates partnerships between vaccine and technology manufacturers and clear regulatory pathways.

    Conclusions:

    • New vaccine packaging and delivery technologies offer significant benefits to immunization supply chains.
    • Early engagement with public-sector stakeholders is vital for ensuring program suitability.
    • Key factors for adoption include cold chain volume, cost-effectiveness, and overall health impact.