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Comparison of single-dose nalbuphine versus tramadol for postoperative pain management in children: a randomized,

Naeem Liaqat1, Sajid Hameed Dar1

  • 1Department of Pediatric Surgery, Services Institute of Medical Sciences/Services Hospital, Lahore, Pakistan.

Korean Journal of Anesthesiology
|April 4, 2017
PubMed

Insights

A single dose of nalbuphine effectively manages acute postoperative pain in children undergoing daycare surgery, showing superiority over tramadol. This approach offers a safe and sufficient option for pediatric pain control.

Area of Science:

  • Pediatric Surgery
  • Pain Management
  • Pharmacology

Background:

  • Effective postoperative pain control is crucial for pediatric daycare procedures.
  • Continuous narcotic analgesics pose risks; single-dose strategies may suffice.

Purpose of the Study:

  • To compare the efficacy of a single dose of nalbuphine versus tramadol for acute postoperative pain management in children undergoing daycare inguinal herniotomy.

Main Methods:

  • Prospective, randomized controlled trial involving 150 pediatric patients (1-12 years).
  • Patients received either nalbuphine (0.2 mg/kg) or tramadol (2 mg/kg) post-surgery.
  • Pain scores were assessed at 0, 1, 2, 4, and 8 hours; rescue analgesic use was recorded.

Main Results:

  • Nalbuphine group showed significantly lower pain scores at 0 and 1 hour post-surgery (P < 0.05).
  • Fewer patients in the nalbuphine group required rescue analgesics (12.0% vs. 21.3%, P = 0.051).
  • Mean time to rescue analgesic requirement was longer in the nalbuphine group (6.5h vs. 5.3h).

Conclusions:

  • A single dose of nalbuphine is sufficient and superior to tramadol for pediatric postoperative pain management in daycare settings.
  • Nalbuphine provides effective and potentially safer acute pain relief compared to tramadol in this patient population.
Abstract

Keywords:
ChildInguinal herniaNalbuphinePostoperative painTramadol

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