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Related Experiment Videos

Early Repolarization in Normal Adolescents is Common.

Humera Ahmed1, Richard J Czosek2, David S Spar2

  • 1Heart Institute, Cincinnati Children's Hospital, 3333 Burnet Avenue, ML 2003, Cincinnati, OH, 45206, USA. humera.ahmed@gmail.com.

Pediatric Cardiology
|April 4, 2017
PubMed
Summary

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Early repolarization pattern (ERP) is common in healthy adolescents, found in 40% of subjects. This electrocardiogram finding did not correlate with increased left ventricular mass or concerning family history in this study population.

Area of Science:

  • Pediatric Cardiology
  • Electrophysiology
  • Preventive Cardiology

Background:

  • The early repolarization pattern (ERP) on electrocardiogram (ECG) is linked to sudden cardiac death in adults with normal hearts.
  • The prevalence and clinical significance of ERP in pediatric populations remain largely unknown.
  • Understanding ERP in adolescents is crucial for assessing potential cardiac risks.

Purpose of the Study:

  • To determine the prevalence of ERP in healthy adolescents.
  • To identify demographic and clinical characteristics associated with ERP.
  • To investigate the correlation between ERP, left ventricular (LV) mass, and family history of cardiac events.

Main Methods:

  • Secondary analysis of data from 575 healthy adolescents undergoing ECG and echocardiography.
Keywords:
CardiologyEarly repolarizationPediatricsSudden deathSyncope

Related Experiment Videos

  • ERP defined by specific QRS-terminal notching/slurring and ST-junction elevation criteria.
  • Comparison of LV mass and family history (sudden death, arrhythmia, ICD/pacemaker) between subjects with and without ERP.

    • Main Results:

    • ERP was present in 40% of subjects, predominantly in inferior and/or lateral leads.
    • No significant differences were found in gender, race, age, syncope history, LV mass, or family history between groups.
    • A higher proportion of subjects with ERP participated in football (34% vs. 13%).

    Conclusions:

    • Early repolarization pattern is a common finding in healthy adolescents.
    • In this cohort, ERP did not correlate with increased LV mass or adverse personal/family cardiac history.
    • Further longitudinal studies are needed to ascertain the long-term mortality risk associated with childhood ERP.