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RECENT ADVANCES IN PHARMACEUTICAL RHEOLOGY.

B W Barry1

  • 1Dept. of Pharmacy, Portsmouth Polytechnic, Portsmouth, England.

Journal of Texture Studies
|April 4, 2017
PubMed
Summary
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This review covers pharmaceutical rheology advancements since 1965, focusing on powders, suspensions, semi-solids, emulsions, suppositories, and aerosols. It synthesizes 292 references to detail material properties and behaviors.

Area of Science:

  • Pharmaceutical Sciences
  • Materials Science
  • Physical Chemistry

Background:

  • The field of rheology is crucial for understanding and controlling the physical properties of pharmaceutical formulations.
  • Significant developments in pharmaceutical rheology have occurred since 1965, necessitating a comprehensive review.

Purpose of the Study:

  • To review and synthesize significant advances in the rheology of pharmaceutical and allied materials since 1965.
  • To provide a structured overview of rheological considerations for various pharmaceutical dosage forms.

Main Methods:

  • A comprehensive literature review was conducted, analyzing 292 references.
  • The review categorizes information based on material type and pharmaceutical application.

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Main Results:

  • Key advances in the rheology of powders, suspensions, semi-solids (creams, ointments), emulsions, suppositories, pessaries, and foam aerosols are detailed.
  • The review highlights the evolution of understanding material properties and their impact on formulation performance.

Conclusions:

  • This review consolidates a significant body of knowledge on pharmaceutical rheology over several decades.
  • It serves as a valuable resource for researchers and formulators working with diverse pharmaceutical materials.