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STRUCTURAL, RHEOLOGICAL AND TEXTURAL PROPERTIES OF SOFT PARAFFINS.

B W Barry1, A J Grace1

  • 1School of Pharmacy, Portsmouth Polytechnic, Portsmouth, England.

Journal of Texture Studies
|April 4, 2017
PubMed
Summary
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This review critically appraises rheological testing methods for soft paraffins and petrolatums. It covers their chemical nature, structure, and textural properties, offering insights into skin application conditions.

Area of Science:

  • Materials Science
  • Physical Chemistry
  • Pharmaceutical Sciences

Background:

  • Soft paraffins and petrolatums are widely used in various industries, particularly pharmaceuticals.
  • Understanding their rheological properties is crucial for formulation and application.
  • Existing literature provides extensive data but lacks a consolidated review of rheological assessment.

Purpose of the Study:

  • To critically review the rheological properties of soft paraffins and petrolatums.
  • To appraise current rheological testing methodologies.
  • To discuss formulation, standardization, and application-related properties.

Main Methods:

  • Comprehensive literature review of 119 references.
  • Critical appraisal of penetrometry, continuous shear viscometry, oscillatory testing, and creep analysis.

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  • Discussion of chemical nature, microscopic structure, and textural properties.
  • Main Results:

    • Identification of key rheological behaviors of soft paraffins.
    • Evaluation of the strengths and limitations of various rheological testing methods.
    • Presentation of a master curve for rheological conditions during skin spreading.

    Conclusions:

    • Standardization and critical evaluation of rheological methods are essential for soft paraffin characterization.
    • Rheological properties significantly influence the performance and application of these materials.
    • Further research can optimize formulation and predict performance based on rheological data.