Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Posterior parietal cortex contains a command apparatus for hand movements.

Jean-Alban Rathelot1,2,3,4, Richard P Dum1,2,3,4, Peter L Strick5,2,3,4

  • 1University of Pittsburgh Brain Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261.

Proceedings of the National Academy of Sciences of the United States of America
|April 5, 2017
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Consensus Paper: Models of Cerebellar Functions.

Cerebellum (London, England)·2026
Same author

Spatial, transcriptomic and epigenomic analyses link dorsal horn neurons to chronic pain genetic predisposition.

bioRxiv : the preprint server for biology·2025
Same author

A molecular and spinal circuit basis for the functional segregation of itch and pain.

bioRxiv : the preprint server for biology·2025
Same author

Multiple cortical systems influence a single vibrissa muscle.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

Predecompression and postdecompression cognitive and affective changes in Chiari malformation type I.

Journal of neurosurgery·2025
Same author

Spatial, transcriptomic, and epigenomic analyses link dorsal horn neurons to chronic pain genetic predisposition.

Cell reports·2024

Researchers found that a specific area in the posterior parietal cortex directly controls hand movements. This region contains neurons linked to the spinal cord, influencing finger and wrist actions.

Area of Science:

  • Neuroscience
  • Motor Control
  • Parietal Lobe Function

Background:

  • The posterior parietal cortex was hypothesized to house a
  • command apparatus
  • for hand control in extrapersonal space.

Purpose of the Study:

  • To investigate the role of a lateral region within area 5 of the posterior parietal cortex in hand movement control.
  • To identify corticospinal neurons directly linked to hand movements.

Main Methods:

  • Electrical stimulation of the lateral region of area 5.
  • Tracing corticospinal neuron projections to spinal cord.
  • Electrophysiological recording of neuronal connections to motoneurons.

Main Results:

Keywords:
cerebral cortexmotor controlmotor systemsmovement control

Related Experiment Videos

  • Electrical stimulation evoked finger and wrist movements.
  • Corticospinal neurons in area 5 project to spinal interneurons innervating hand motoneurons.
  • Area 5 neurons exhibit prominent disynaptic connections with hand motoneurons.

Conclusions:

  • A lateral region within area 5 functions as a motor area.
  • Corticospinal neurons in this area are directly involved in hand movement control.
  • This region acts as a command apparatus for hand operations.