Related Experiment Video
Updated: Jul 23, 2026

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells
Published on: September 12, 2019
A 64-Year-Old Woman with Chest Pain, Limb Weakness, and Endometrial Cancer
Simon Ponthus1, Omar Kherad1, Nicole Petriccioli1
1Internal Medicine Department, Hôpital de la Tour, Geneva, Switzerland.
Abstract:
Necrotizing autoimmune myopathy (NAM) is a rare subgroup of idiopathic inflammatory myopathies (IIM). This pathology usually affects proximal limb muscles and in some cases the myocardium. Patients usually display proximal limb weakness. Muscular biopsy is required to confirm the diagnosis. We report the case of a 64-year-old woman with an atypical first presentation of NAM, manifested by chest pain in the context of metastatic endometrial cancer. The diagnosis of NAM was however made when she returned a second time with proximal limb weakness. A treatment with prednisone was then initiated, to which rituximab was rapidly associated, beside a specific chemotherapy.
Related Concept Videos
Disorders of the Female Reproductive System
Menopause
Mitral Valve Prolapse II: Assessment and Management
Endocarditis IV: Nursing Management
Coronary Artery Disease III: Clinical Manifestations
Angina III: Clinical Manifestations and Assessment

