Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Surface cross-linked UHMWPE using peroxides.

Rizwan M Gul1,2, Katharina Fung1, Brinda N Doshi1

  • 1Harris Orthopedic Laboratory, Massachusetts General Hospital, 55 Fruit St. GRJ 1206, Boston 02114, Massachusetts.

Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
|April 5, 2017
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

In-vitro study and in-vivo zebrafish model to minimize the toxic effects of implant (CoCrMo particles) by antioxidants.

Toxicology in vitro : an international journal published in association with BIBRA·2026
Same author

The 2025 International Consensus Meeting on Musculoskeletal Infection: Research Priorities and Future Directions.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society·2026
Same author

A dynamic device to simulate intraarticular drug-release kinetics.

International journal of pharmaceutics·2026
Same author

2025 International Consensus Meeting on Musculoskeletal Infection: Summary From Biofilm Workgroup on Treatment of Biofilm-Related Infection and Preclinical Models.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society·2026
Same author

Dual-drug releasing PEG-PLA hydrogels with tunable degradation for sustained local analgesia and anti-inflammatory therapy in a rat fracture/osteotomy model.

Biomaterials·2026
Same author

Deep Learning Enhances Weightbearing CT Detection of Lisfranc Instability: A FIXUS-AI Ankle Insight 3D Algorithm.

Cureus·2026
Same journal

Repurposing Metformin to Promote Fracture Callus Maturation via AMPK-Driven Metabolic Activation.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society·2026
Same journal

Biomechanical Assessment of Functional Tasks Beyond Level Walking Following Total Hip Arthroplasty: A Scoping Review.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society·2026
Same journal

Gait Characteristics and Intersegmental Foot and Ankle Motion in Patients With Neglected Achilles Tendon Rupture.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society·2026
Same journal

A Biomechanical Proof-of-Concept Study of Scaffold-Augmented Distraction Osteogenesis Using 3D-Printed Hyperelastic Bone™ in a Rabbit Tibial Lengthening Model.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society·2026
Same journal

Predicting Primary Stability of Stemless TSA From Preoperative Bone Density and Surgical Factors.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society·2026
Same journal

Locking Compression Plate Versus Dynamic or Limited Contact Dynamic Compression Plate Fixation for Forearm Fractures: A Systematic Review and Meta-Analysis.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society·2026
See all related articles

Surface crosslinking of ultra-high molecular weight polyethylene (UHMWPE) with vitamin E improves wear resistance. This novel technique enhances orthopedic implant durability without compromising mechanical strength.

Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Orthopedic Engineering

Background:

  • Ultra-high molecular weight polyethylene (UHMWPE) is a key material for orthopedic implants.
  • Improving UHMWPE's wear performance is crucial for extending implant lifespan.
  • Bulk crosslinking reduces mechanical properties, necessitating surface-specific treatments.

Purpose of the Study:

  • To develop and evaluate a novel surface crosslinking technique for UHMWPE/vitamin-E blends.
  • To assess the impact of surface crosslinking on wear rate and oxidation resistance.
  • To compare the efficacy of two different organic peroxides for surface modification.

Main Methods:

  • Consolidated UHMWPE/vitamin-E blends were treated with organic peroxides.
  • Peroxide diffusion into the polymer surface was followed by thermal decomposition.
Keywords:
biomaterialship and knee arthroplastyimplant wearpolyethelene and biomaterials

Related Experiment Videos

  • Surface crosslink density and wear rate were quantified.
  • Oxidation resistance was evaluated with the addition of vitamin E.
  • Main Results:

    • Both tested peroxides successfully induced surface crosslinking in UHMWPE/vitamin-E blends.
    • Surface crosslinked samples exhibited significantly improved wear resistance.
    • Wear resistance was comparable to state-of-the-art highly crosslinked UHMWPE.
    • Incorporation of vitamin E enhanced the material's oxidation resistance.

    Conclusions:

    • The novel surface crosslinking technique effectively enhances UHMWPE wear performance.
    • This method offers a promising approach for developing durable orthopedic implants.
    • Combining surface crosslinking with vitamin E provides dual benefits of wear and oxidation resistance.