Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Autonomic neuropathy in leprosy.

A Ramachandran1, P N Neelan

  • 1Central Leprosy Teaching & Research Institute, Chengalpattu, Tamil Nadu.

Indian Journal of Leprosy
|October 1, 1987
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

DeeppestNet: An end-to-end framework for high-performance crop pest recognition.

Computational biology and chemistry·2026
Same author

Real-World Evaluation of Early Initiation of Dapagliflozin and Sitagliptin Combination Therapy in the Management of Type 2 Diabetes Mellitus (REALIZE Study).

Cureus·2025
Same author

A Randomized Study Comparing Mini PCNL and RIRS for Renal Stones between 8 mm and 15 mm - A Single Institutional Experience.

Nigerian journal of clinical practice·2025
Same author

Appendectomy and asthma: a search for an association in older subjects.

The Medical journal of Malaysia·2024
Same author

Gastrojejunostomy as a treatment for gastric outflow disorders in four adult horses.

Australian veterinary journal·2023
Same author

A metagenomic-based study of two sites from the Barbadian reef system.

Coral reefs (Online)·2023

Leprosy commonly causes autonomic neuropathy, affecting cardiovascular and genital systems. This nerve damage, particularly to the parasympathetic system, worsens with disease duration.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Autonomic Nervous System Research

Background:

  • Leprosy, a chronic infectious disease, can lead to various complications.
  • Autonomic dysfunction is increasingly recognized in infectious diseases.

Purpose of the Study:

  • To investigate the prevalence and characteristics of autonomic neuropathy in leprosy patients.
  • To assess the involvement of both sympathetic and parasympathetic nervous systems.

Main Methods:

  • Autonomic function tests were performed on 21 leprosy patients (borderline lepromatous and lepromatous types).
  • Cardiovascular and genital autonomic functions were evaluated.
  • Five healthy volunteers served as controls.

Main Results:

Related Experiment Videos

  • Autonomic function tests revealed significant involvement of the cardiovascular and genital systems in leprosy patients.
  • The incidence of autonomic neuropathy ranged from 14.3% to 57% across different tests.
  • Parasympathetic (vagus nerve) involvement was more common and occurred earlier than sympathetic damage.
  • Sympathetic damage was consistently associated with parasympathetic damage.
  • Increased severity of autonomic neuropathy correlated with longer leprosy duration.

Conclusions:

  • Autonomic neuropathy is a common complication in leprosy, affecting multiple systems.
  • Parasympathetic dysfunction is an early and frequent finding, often preceding or accompanying sympathetic damage.
  • The findings highlight the systemic impact of leprosy and suggest similarities with autonomic neuropathy in diabetes mellitus.