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Process Principles for Large-Scale Nanomanufacturing.

Sven H Behrens1, Victor Breedveld1, Maritza Mujica1

  • 1School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332-0100;

Annual Review of Chemical and Biomolecular Engineering
|April 5, 2017
PubMed
Summary

Achieving scalable nanomanufacturing requires overcoming key barriers by adopting iterative synthesis, assembly, separation, and sorting processes. Designing these processes must consider unique nanoscale phenomena for practical application.

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Area of Science:

  • Materials Science
  • Chemical Engineering
  • Nanotechnology

Background:

  • Nanomanufacturing, the creation of large products from nanoscale components, faces significant scalability and versatility challenges.
  • Current methods often fall short of the demands for true industrial-scale production.

Purpose of the Study:

  • To identify critical barriers hindering large-scale nanomanufacturing.
  • To propose effective strategies and process designs for overcoming these limitations.

Main Methods:

  • Analysis of existing nanomanufacturing limitations.
  • Proposal of a process flow analogous to chemical manufacturing, involving iterative synthesis/assembly and separation/sorting.
  • Consideration of nanoscale-specific phenomena in process design.
Keywords:
nanomanufacturingnanotechnologyprocess designscale-up

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Main Results:

  • Identification of key challenges in scaling nanomanufacturing.
  • A framework for nanomanufacturing systems based on iterative unit operations.
  • Emphasis on the need to integrate nanoscale phenomena into process design.

Conclusions:

  • Scalable nanomanufacturing necessitates a paradigm shift towards integrated, iterative processes.
  • Overcoming barriers requires careful selection of process break points and large-scale synthesis techniques.
  • Future nanomanufacturing success depends on addressing unique nanoscale characteristics within the overall process flow.