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Now UCP(rotein), Now You Don't: UCP1 Is Not Mandatory for Thermogenesis
1Department of Biology, University of Padova, 35121 Padova, Italy; CNR Neuroscience Institute, 35121 Padova, Italy.
Cell Metabolism
|April 6, 2017
Abstract:
Adipocyte-targeted therapies could potentially combat obesity and metabolic disorders; however, our understanding of adipogenesis and the characterization of the various adipose tissues are incomplete. In this issue, Bertholet et al. (2017) report the existence of two types of heat-producing beige-like adipocytes, those with and those without the mitochondrial uncoupling protein 1 (UCP1).