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Poncet's disease: two case reports.

Fatima Adhi1, Rabia Hasan1, Mehreen Adhi1

  • 1Aga Khan University Karachi, Karachi, Pakistan.

Journal of Medical Case Reports
|April 7, 2017
PubMed
Summary
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Poncet's disease, a rare joint pain presentation of tuberculosis, can mimic rheumatological conditions. Early diagnosis and anti-tuberculous therapy are crucial for managing this debilitating joint pain.

Area of Science:

  • Rheumatology
  • Infectious Diseases
  • Orthopedics

Background:

  • Poncet's disease is a rare manifestation of active tuberculosis, presenting as polyarthropathy (joint pain) affecting multiple joints.
  • This joint pain can be the initial and sole symptom of tuberculosis, preceding more typical pulmonary or extrapulmonary signs.
  • Polyarthropathy in tuberculosis can be misdiagnosed as common rheumatological diseases due to similar clinical presentations.

Observation:

  • Two cases are presented: a 25-year-old woman and a 45-year-old man, both with active tuberculosis.
  • Polyarthralgia was the primary and isolated symptom for several months in both patients.
  • Pulmonary and pleural manifestations developed later in both cases, confirming active tuberculosis.

Findings:

  • Both patients experienced significant improvement in joint pain and overall condition with anti-tuberculous therapy.
Keywords:
Poncet’s diseaseTuberculosisTuberculous rheumatismpolyarthritis

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  • A 6-month course of anti-tuberculous medication was effective in treating the disease.

    • Implications:

    • Tuberculosis should be considered in the differential diagnosis for patients presenting with unusual polyarthralgia, especially in endemic areas.
    • Recognizing Poncet's disease as a potential presentation of tuberculosis is vital for timely and appropriate treatment.
    • Prompt diagnosis and treatment of tuberculosis-related joint pain can prevent long-term morbidity and improve patient mobility.