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Potential Use of Cyclodextrins as Drug Carriers and Active Pharmaceutical Ingredients
Hidetoshi Arima1, Keiichi Motoyama, Taishi Higashi
1Graduate School of Pharmaceutical Sciences, Kumamoto University.
Chemical & Pharmaceutical Bulletin
|April 7, 2017
Abstract:
Cyclodextrins (CyDs) are extensively used in various fields, and especially have been widely utilized as pharmaceutical excipients and drug carriers in the pharmaceutical field. Owing to the multi-functional and biocompatible characteristics, CyDs can improve the undesirable properties of drug molecules. This review outlines the current application of CyDs in pharmaceutical formulations, focusing on their use as CyD-based drug carriers for several kinds of drugs. Additionally, CyDs have great potential as active pharmaceutical ingredients against various diseases with few side effects.