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Related Concept Videos

Somatosensation01:33

Somatosensation

The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
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Depth Perception and Spatial Vision

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Related Experiment Video

Updated: Jul 26, 2026

Measuring Attention and Visual Processing Speed by Model-based Analysis of Temporal-order Judgments
13:00

Measuring Attention and Visual Processing Speed by Model-based Analysis of Temporal-order Judgments

Published on: January 23, 2017

A neuroanatomical model of space-based and object-centered processing in spatial neglect.

Elena Pedrazzini1,2, Armin Schnider3,4, Radek Ptak5,6,7

  • 1Laboratory of Cognitive Neurorehabilitation, Faculty of Medicine, University of Geneva, Geneva, Switzerland. ele.pedrazzini@gmail.com.

Brain Structure & Function
|April 7, 2017
PubMed
Summary

Right-hemisphere damage causes distinct spatial neglect deficits. Object-centered processing relies on superior parietal damage, while space-based processing involves inferior parietal damage, indicating partly independent systems.

Keywords:
Attention networkFrontal lobeParietal lobeSpatial neglectVisual attention

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Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Neurology

Background:

  • Visual attention operates in space-based and object-centered frames.
  • Right-hemisphere damage can cause dissociable deficits in these processing types, contributing to spatial neglect heterogeneity.
  • Previous research suggested distinct neuroanatomical correlates for object-centered vs. space-based processing deficits, but with limitations.

Purpose of the Study:

  • To test a theoretical model of spatial neglect, examining the relationship between space- and object-based processing deficits and specific neuroanatomical predictors.
  • To investigate whether object-centered and space-based processing represent a unique latent variable or two distinct variables in spatial neglect.

Main Methods:

  • One hundred and one right-hemisphere-damaged patients underwent neuropsychological testing and structural brain imaging.
  • Two structural equation models were used to analyze the relationship between neglect measures and damage to the temporal-parietal junction, intraparietal cortex, insula, and middle frontal gyrus.
  • Object-centered processing was assessed via line bisection and single-word reading; space-based processing was assessed via cancelation tasks.

Main Results:

  • A model treating object-centered and space-based processing as distinct variables demonstrated superior explanatory power.
  • Damage to the intraparietal sulcus significantly predicted object-centered processing deficits.
  • Damage to the temporal-parietal junction significantly predicted space-based processing deficits.
  • Despite partial independence, space-based and object-centered processing were strongly intercorrelated.

Conclusions:

  • Object-centered and space-based deficits in spatial neglect are partly independent.
  • Object-centered deficits are associated with superior parietal damage (intraparietal sulcus).
  • Space-based deficits are associated with inferior parietal damage (temporal-parietal junction).
  • These findings refine our understanding of the neural basis of spatial neglect and visual attention.