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Related Experiment Videos

[Moxiflaxin and iris transillumination].

A Broens1, N Collignon1

  • 1Service d'Ophtalmologie, CHU de Liège. Site Sart-Tilman, 4000 Liège, Belgique.

Revue Medicale De Liege
|April 7, 2017
PubMed
Summary

Bilateral Acute Iris Transillumination (BAIT) is a newly identified condition causing iris pigment dispersion and depigmentation. This case report highlights a potential link between systemic moxifloxacin use and the development of BAIT.

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Area of Science:

  • Ophthalmology
  • Pharmacology

Background:

  • Bilateral Acute Iris Transillumination (BAIT) is a recently recognized clinical entity.
  • It presents with acute pigment dispersion in the anterior chamber and angle, iris stroma depigmentation, and permanent iris transillumination.
  • BAIT can mimic symptoms of uveitis, posing a diagnostic challenge.

Observation:

  • This report details a case of BAIT occurring bilaterally.
  • The patient developed BAIT following the administration of systemic moxifloxacin.
  • Previous literature suggests a possible association between oral moxifloxacin and BAIT.

Findings:

  • The observed case confirms the potential for moxifloxacin-induced BAIT.
  • The clinical presentation included characteristic signs of iris transillumination and pigment dispersion.
  • The condition resulted in permanent changes to the iris.

Implications:

  • This case underscores the importance of considering moxifloxacin as a potential causative agent for BAIT.
  • Ophthalmologists should be aware of this association when diagnosing patients with unexplained iris transillumination.
  • Further research is warranted to elucidate the precise mechanism and prevalence of moxifloxacin-associated BAIT.
Keywords:
Iris transilluminationMoxifloxacinPigment dispersionUveitis

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