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[Inflammatory sequelae after adenovirus infection]
O P van Bijsterveld1, O L van Hemel
1Koninklijk Nederlands Gasthuis voor Ooglijders, Utrecht, Pays-Bas.
Abstract:
Adenovirus infections are common. The period of virus replication is short, hardly ever exceeding two weeks. In 216 patients we studied the post-inflammatory period after infection with adenovirus types 8, 4, 3, 7, 19 and 37, in some patients up to three years. In 49.5%, the initial infection also involved the cornea, in 79.5% bilaterally. In 50.5% there was only follicular conjunctivitis. The post-inflammatory period is most annoying as rather frequently a considerable period of chronic eye irritation can be expected. In our study the number of cases with post-infectious ocular irritation tended to decrease slowly. Treatment with 0.5% methylcellulose was of little help to alleviate the ocular irritation.
Insights
Adenovirus infections can cause prolonged eye irritation, even after the initial viral replication period ends. This study observed chronic ocular discomfort in many patients following adenovirus infection, with limited relief from methylcellulose treatment.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Virology