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Repeal and Replace: Adipocyte Regeneration in Wound Repair
1Departments of Molecular, Cellular and Developmental Biology and Dermatology, Yale University, New Haven, CT 06520, USA.
Cell Stem Cell
|April 8, 2017
Abstract
None:
Adipocyte precursor cells generate lipid-filled mature adipocytes in multiple tissues during a high-fat diet and in skin during hair follicle growth. In Science, Plikus et al. report that myofibroblasts can generate lipid-filled adipocytes in large skin wounds that regenerate hair follicles, suggesting a new source of adipogenic progenitor cells.