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Evaluation of calcium hydrogen carbonate mesoscopic crystals as a disinfectant for influenza A viruses
Ryuji Nakashima1, Masaomi Kawamoto1, Shigeru Miyazaki1
1Research Institute for Animal Science in Biochemistry and Toxicology, Midori-ku, Sagamihara, Kanagawa 252-0132, Japan.
Abstract:
In this study, the virucidal effect of a novel electrically charged disinfectant CAC-717 was investigated. CAC-717 is produced by applying an electric field to mineral water containing calcium hydrogen carbonate to generate mesoscopic crystals. Virus titration analysis showed a >3 log reduction of influenza A viruses after treatment with CAC-717 for 1 min in room temperature, while infectivity was undetectable after 15 min treatment. Adding bovine serum albumin to CAC-717 solution did not affect the disinfectant effect. Although CAC-717 is an alkaline solution (pH=12.39), upon contact with human tissue, its pH becomes almost physiological (pH 8.84) after accelerated electric discharge, which enables its use against influenza viruses. Therefore, CAC-717 may be used as a preventative measure against influenza A viruses and for biosecurity in the environment.