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Retinoic binding in melanomas of the eye and in normal choroid
F Daxecker1, C Marth, G Daxenbichler
1Department of Ophthalmology, University of Innsbruck, Austria.
Cancer Letters
|July 1, 1988
Abstract:
Binding proteins for retinoic acid (cellular retinoid acid binding protein, CRABP), and for vitamin A (cellular retinol binding protein, CRBP) have been demonstrated in various cell types; these binding proteins display the characteristics of receptors. In the present study CRABP and CRBP levels were measured in 9 melanomas of the choroid. CRABP was detected in 2 of the melanomas, whereas CRBP was measurable in 1 melanoma. In comparison samples of normal choroid contained CRABP and CRBP in all cases investigated.