Related Experiment Video
Updated: Jul 27, 2026

Assessing Activity-based Anorexia in Mice
Published on: May 14, 2018
Now you see it, Now you don't: compulsive exercise in adolescents with an eating disorder
Johanna Levallius1,2, Christina Collin1,2, Andreas Birgegård1,2
1Department of Clinical Neuroscience, Resource Center for Eating Disorders, Center for Psychiatry Research, Karolinska Institutet, SE-113 64 Stockholm, Sweden.
Background:
Compulsive exercise (CE) has been proposed as significant in the etiology, development and maintenance of eating disorders (EDs), resulting in more severe and enduring pathology. However, few studies have investigated CE longitudinally in adolescents with EDs. We aimed to test if adolescents show the same associations between CE and other clinical variables as previous research has found in adults.
Methods:
Three thousand one hundred sixteen girls and 139 boys from a clinical ED database were investigated regarding prevalence and frequency of CE and its relation to psychiatric symptoms, associated features and outcome. Denial of illness is common among adolescents and was therefore adjusted for.
Results:
Adjusted CE prevalence in girls was 44%, and CE was most prevalent in bulimia nervosa. As previously found in adults, those with CE scored significantly higher than non-CE on total ED severity, level of restriction and negative perfectionism. However, there were only minor differences between CE and non-CE patients on emotional distress, hyperactivity, suicidality and self-esteem. Among boys, adjusted CE prevalence was 38%, and CE boys scored significantly higher than non-CE on total ED severity. Initial CE did not influence 1-year outcome, although cessation of CE was associated with remission.
Conclusions:
CE is a common clinical feature in adolescents with EDs and cessation is associated with remission. When controlling for denial of illness, CE had less detrimental impact than predicted. We recommend controlling for denial in studies on ED adolescents and further exploration of classification and treatment implications of CE.
Related Concept Videos
Obesity
Obsessive-Compulsive Disorder
Anorexia Nervosa
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
Bulimia Nervosa
Binge Eating Disorders
Conduct Disorder

