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[Physical activity and breast cancer].
Karol Ramírez1, Francisco Acevedo2, María Elisa Herrera2
1UDA Ciencias de la Salud, Pontificia Universidad Católica de Chile, Santiago, Chile.
Revista Medica De Chile
|April 11, 2017
Summary
Regular physical activity (PA) is linked to lower breast cancer (BC) incidence and recurrence. This review explores the evidence and biological basis for PA
Area of Science:
- Oncology
- Epidemiology
- Exercise Science
Background:
- Breast cancer (BC) is the leading cause of cancer death in women in Chile.
- Estrogenic stimulation is a primary risk factor, but environmental and lifestyle factors also play a role.
- Epidemiological studies indicate a direct correlation between physical activity (PA) and BC incidence and recurrence.
Purpose of the Study:
- To review epidemiological evidence linking physical activity (PA) and breast cancer (BC).
- To explore the biological mechanisms underlying the relationship between PA and BC.
- To examine interventional studies and practical applications of PA for BC patients.
Main Methods:
- Systematic review of epidemiological studies on PA and BC.
- Analysis of biological pathways affected by PA relevant to BC.
- Review of clinical trials investigating PA interventions in cancer patients.
Main Results:
- Consistent evidence demonstrates that higher levels of PA are associated with reduced risk of BC.
- PA influences BC through mechanisms including hormone regulation, inflammation, and immune function.
- Interventional studies show that supervised PA improves quality of life and may improve prognosis in BC patients.
Conclusions:
- Physical activity is a crucial modifiable factor in breast cancer prevention and management.
- PA offers significant benefits for cancer patients, improving treatment outcomes and overall well-being.
- The findings support integrating PA recommendations into standard care for breast cancer survivors, serving as a model for other cancers.