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[IgG4 associated nephritis and recurrent hemoptysis: Case report]
Daniel Erlij1, Ángela Rivera1, Juan Carlos Maya1
1Sección de Reumatología, Servicio de Medicina Hospital del Salvador, Universidad de Chile, Santiago, Chile.
Revista Medica De Chile
|April 11, 2017
Summary
Immunoglobulin G4 (IgG4) related disease can affect multiple organs, including the kidneys and lungs. This case highlights IgG4-associated interstitial nephritis presenting with hemoptysis and renal dysfunction.
Area of Science:
- Nephrology
- Pulmonology
- Rheumatology
Background:
- Immunoglobulin G4 (IgG4) related disease is a chronic, fibrosing condition affecting various organs.
- While commonly involving the pancreas, salivary glands, and lymph nodes, it can also manifest as interstitial nephritis and lung disease.
Observation:
- A 58-year-old male presented with a four-year history of hemoptysis, hematuria, and proteinuria.
- His renal dysfunction was responsive to corticosteroid therapy.
Findings:
- Renal biopsy confirmed the diagnosis of IgG4-associated interstitial nephritis.
- Lung involvement was deemed secondary to the systemic IgG4 related disease.
Implications:
- This case underscores the importance of considering IgG4 related disease in patients with unexplained renal and pulmonary symptoms.
- Early diagnosis and treatment with corticosteroids can lead to favorable outcomes in IgG4-associated kidney and lung involvement.