Related Experiment Video
Updated: Jul 19, 2026

06:52
The use of Biofeedback in Clinical Virtual Reality: The INTREPID Project
Published on: November 12, 2009
A Randomized, Head-to-Head Study of Virtual Reality Exposure Therapy for Posttraumatic Stress Disorder
Robert N McLay1, Alicia Baird2, Jennifer Webb-Murphy3
11 San Diego County Mental Health , San Diego, California.
Cyberpsychology, Behavior and Social Networking
|April 11, 2017
Summary
Virtual reality exposure therapy (VRET) and control exposure therapy (CET) both effectively treat combat-related PTSD in service members. However, VRET did not show additional benefits over CET and had higher dropout rates.
Area of Science:
- Psychiatry
- Psychology
- Military Medicine
Background:
- Virtual reality exposure therapy (VRET) shows promise for treating combat-related PTSD in active duty service members.
- Randomized controlled trials support VRET, but its comparative effectiveness against traditional methods needs further investigation.
Purpose of the Study:
- To compare the effectiveness of VRET versus control exposure therapy (CET) for combat-related PTSD.
- To determine if virtual reality technology offers additional benefits beyond standard exposure therapy.
Main Methods:
- A comparative effectiveness study randomly assigned service members with combat-related PTSD to nine weeks of VRET or CET.
- Clinician-Administered PTSD Scale (CAPS) assessed PTSD symptom improvement one week and three months post-treatment.
- Assessors were blinded to treatment conditions, but therapists were not.
Main Results:
- Both VRET and CET led to significant PTSD symptom improvement.
- No statistically significant differences in outcomes were observed between VRET and CET groups.
- Dropout rates were higher in the VRET group compared to the CET group.
Conclusions:
- Exposure therapy is effective for treating combat-related PTSD in service members.
- The inclusion of virtual reality in exposure therapy did not demonstrate additional benefits over traditional CET.
- Further research may explore factors contributing to higher dropout rates in VRET.

