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[A pilot study to explore a registry method for acute cardiovascular events]
1Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing 100005, China.
Insights
This study developed a registry method for acute cardiovascular events in China, finding high incidence and mortality rates. Primary care physicians are crucial for integrated health monitoring systems.
Area of Science:
- Cardiovascular Epidemiology
- Public Health Surveillance
- Registry Methodology
Background:
- Acute cardiovascular events pose a significant public health challenge globally.
- Effective registry methods are essential for accurate epidemiological data collection and surveillance.
Purpose of the Study:
- To develop and evaluate a comprehensive registry method for acute cardiovascular events in a large-scale Chinese cohort.
- To determine the incidence and mortality rates of acute cardiovascular events in the study population.
Main Methods:
- A community-based Kazakh cohort of 1,668 individuals in Altay, Xinjiang, was established.
- A multi-stage registry approach was employed, including hospital-based searches, community supplementary registries, and surveys to minimize false negatives.
- Acute cardiovascular events (acute myocardial infarction, sudden cardiac death, incident stroke) were tracked from October 2012 to June 2016.
Main Results:
- A total of 46 acute cardiovascular events were recorded, with strokes being the most common (36 cases).
- The standardized incidence rate was 926 per 100,000 people, and the standardized mortality rate was 272 per 100,000 people.
- The registry method successfully identified events, with 60.9% found through hospital records and 39.1% via community-based registries.
Conclusions:
- The developed registry method is effective for capturing acute cardiovascular events in large-scale populations.
- Primary care physicians play a vital role in integrated health monitoring systems, combining preventive and clinical medicine with governmental resources.
Abstract:
Objective: To explore a registry method for acute cardiovascular events in large-scale fields across China. Methods: This study was based on a community-based Kazakh cohort, including 1 668 persons with complete baseline data, conducted in Altay, Xinjiang. Acute cardiovascular events included acute myocardial infarction(ICD-10: I21-I22), sudden cardiac death (I46.1), and incident stroke (I60-I64) that occurred during the period from Oct 1, 2012 to Jun 30, 2016. There were three stages, a hospital-based search for checking medical records of inpatients in all four local hospitals, a community-based supplementary registry, and an extra survey for reducing false negatives, to complete this registry. The incidence referred to all events within one year per 100 000 people and mortality rate was the number of fatal events within 28 days per 100 000 people. The incidence and mortality was standardized with the weights from distribution of age and gender in the Sixth National Census of China. Results: Forty two cases with 46 acute cardiovascular events including 7 acute myocardial infarctions, 3 sudden cardiac deaths, and 36 incident strokes were found. The ratio of events was 3.6∶1 for stroke and heart attacks and this ratio was 1.6∶1 for ischemic or hemorrhagic strokes. A total of 28(60.9%) events and 18(39.1%) events were collected in the hospitals and by community-based supplementary registry physicians, respectively. False negatives were not found at the last stage. The crude and standardized incidence rates were 742 and 926 per 100 000 people and the related mortality rates were 194 and 272 per 100 000 people, respectively. Conclusion: Primary Care physicians are"net bottom" of a monitoring system which needs to combine preventive and clinical medicine with all kinds of governmental resources including health and social benefit.